About DESMODA
The way forward is precision-focused and designed to help support accurate dosing for CDI management
DESMODA is the first and only FDA-approved oral liquid desmopressin
DESMODA can be used to treat central diabetes insipidus (CDI), also known as arginine vasopressin deficiency (AVP-D), across all ages to reduce excessive urination and extreme thirst and balance water levels in the body.
As an alternative to desmopressin tablets, nasal sprays, injections, and other liquid options, DESMODA is designed to help reduce dosing variability and complexity. It helps you ensure that each dose is tailored to you or your child’s needs.
Limitations of use: DESMODA is not approved to treat nephrogenic diabetes insipidus.
Why DESMODA is different
The benefits of trusted desmopressin, now in a liquid form that requires no shaking or mixing
DESMODA helps allow doses to be measured accurately and adjusted as needed over time. For adults and caregivers of children with CDI, DESMODA is an oral liquid formulation, which is designed to help provide:
Precision
Helps allow accurate measurement for individualized, prescribed dosing
Flexibility
Helps avoid reliance on tablet splitting, crushing, or other dosing modifications
Consistency
Helps support a measured dose designed to be repeatable
DESMODA is designed to help provide precise, consistent dosing without splitting or crushing tablets
DESMODA is designed to help provide precise, consistent dosing without splitting or crushing tablets
Studies have shown that desmopressin helps people with CDI, also known as AVP-D, keep the right amount of water in their body. This reduces their need to urinate so often. A clinical study showed that liquid DESMODA delivers about the same amount of desmopressin as tablets.
This means DESMODA can successfully:
- Help the body hold on to water
- Lessen the need to urinate as often
Ask your doctor if DESMODA is right for you or your child
What to know when taking DESMODA
Because desmopressin affects how the body holds water, it’s important to watch for signs of the body holding too much water (called water intoxication, water poisoning, or overhydration). This is the main safety concern with DESMODA, as holding too much water can dilute the sodium in the blood, leading to low sodium levels (called hyponatremia). Your or your child’s doctor will monitor sodium levels during treatment with DESMODA.
Signs you or your child may be holding too much water include:
Headache
Nausea or vomiting
Weight gain
Feeling restless
Feeling very tired, weak, or confused
The most common side effects while taking DESMODA include headache, dizziness, nausea, stomach pain, high blood pressure, and diarrhea. Watch for signs of an allergic reaction, including trouble breathing, swelling in the face or throat, or severe rash.
Talk to your doctor if you or your child experience any of these symptoms while taking DESMODA
Learn how to take DESMODA
USE AND IMPORTANT SAFETY INFORMATION
USE
DESMODA (desmopressin acetate) oral solution is a prescription medicine used to treat central diabetes insipidus (CDI) in adults and children.
Limitations of Use
Do not use DESMODA for the treatment of nephrogenic diabetes insipidus.
Who should NOT take DESMODA?
Do not take DESMODA if you:
- Have or have ever had low blood sodium levels (hyponatremia)
- Are allergic to desmopressin or any of the ingredients in DESMODA
- Have moderate to severe reduction in kidney function (creatinine clearance less than 50 mL/min)
IMPORTANT SAFETY INFORMATION
DESMODA can cause low blood sodium levels (hyponatremia), which can be serious and may be life-threatening.
Drinking too much fluid while taking DESMODA can lead to water intoxication and dangerously low sodium levels.
Symptoms of low blood sodium may include: headache, nausea or vomiting, weight gain, tiredness or weakness, confusion, muscle cramps or spasms. Severe symptoms may include seizures, coma, or trouble breathing. Your healthcare provider may recommend limiting how much fluid you drink and may monitor your blood sodium levels during treatment.
Children and older adults may be at higher risk of developing low sodium levels.
DESMODA may cause your body to hold onto (retain) fluid. Tell your healthcare provider if you have heart failure, high blood pressure, or swelling.
Serious allergic reactions, including fatal anaphylaxis, have occurred with desmopressin products. Stop taking DESMODA and seek emergency medical help if you develop symptoms such as trouble breathing, swelling of the face or throat, or severe rash.
DESMODA contains benzoic acid, which could potentially be harmful to low-birth-weight and preterm infants. Use in these patients requires careful monitoring and fluid restriction.
What are the possible side effects of DESMODA?
Other common side effects include GI upset, swelling, high blood pressure, nervous system disorders, and abnormal thinking.
USE AND IMPORTANT SAFETY INFORMATION
USE
DESMODA (desmopressin acetate) oral solution is a prescription medicine used to treat central diabetes insipidus (CDI) in adults and children.
Limitations of Use
Do not use DESMODA for the treatment of nephrogenic diabetes insipidus.
Who should NOT take DESMODA?
Do not take DESMODA if you:
- Have or have ever had low blood sodium levels (hyponatremia)
- Are allergic to desmopressin or any of the ingredients in DESMODA
- Have moderate to severe reduction in kidney function (creatinine clearance less than 50 mL/min)
IMPORTANT SAFETY INFORMATION
DESMODA can cause low blood sodium levels (hyponatremia), which can be serious and may be life-threatening.
Drinking too much fluid while taking DESMODA can lead to water intoxication and dangerously low sodium levels.
Symptoms of low blood sodium may include: headache, nausea or vomiting, weight gain, tiredness or weakness, confusion, muscle cramps or spasms. Severe symptoms may include seizures, coma, or trouble breathing. Your healthcare provider may recommend limiting how much fluid you drink and may monitor your blood sodium levels during treatment.
Children and older adults may be at higher risk of developing low sodium levels.
DESMODA may cause your body to hold onto (retain) fluid. Tell your healthcare provider if you have heart failure, high blood pressure, or swelling.
Serious allergic reactions, including fatal anaphylaxis, have occurred with desmopressin products. Stop taking DESMODA and seek emergency medical help if you develop symptoms such as trouble breathing, swelling of the face or throat, or severe rash.
DESMODA contains benzoic acid, which could potentially be harmful to low-birth-weight and preterm infants. Use in these patients requires careful monitoring and fluid restriction.
What are the possible side effects of DESMODA?
Other common side effects include GI upset, swelling, high blood pressure, nervous system disorders, and abnormal thinking.
Drug interactions
Tell your healthcare provider about all medicines you take. Some medicines may increase the risk of low sodium levels when taken with DESMODA, including certain antidepressants, pain medicines, NSAIDs, and seizure medicines. DESMODA can cause increased blood pressure. Talk to your doctor if you take other medicine that can raise blood pressure.
Please visit DESMODA.com for more information.
You are encouraged to report negative side effects of prescription drugs by contacting Eton Pharmaceuticals, Inc. at 1-855-224-0233 or the U.S. Food and Drug Administration (FDA) at https://www.fda.gov/safety/medwatch or call 1-800-FDA-1088.
Please see full Prescribing Information for more information.